Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRD4 All Species: 11.52
Human Site: T663 Identified Species: 36.19
UniProt: O60885 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60885 NP_055114.1 1362 152219 T663 F E T L K P S T L R E L E R Y
Chimpanzee Pan troglodytes XP_512452 1148 127234 P663 T E T S E S L P P A S L G K E
Rhesus Macaque Macaca mulatta XP_001115820 787 86976 K309 P P G S L E P K A A R L P P M
Dog Lupus familis XP_866354 726 80895 P246 M T V V P P Q P L Q T P P P V
Cat Felis silvestris
Mouse Mus musculus Q9ESU6 1400 155905 T664 F E T L K P S T L R E L E R Y
Rat Rattus norvegicus Q6MGA9 798 88032 S319 L P P M R R E S G R P I K P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025845 729 80371 S251 T S G E S S P S A T L L E A K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13709 2038 205327 T1005 F E T L K P S T L R E L E S Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.1 31.2 51.8 N.A. 93.1 31.7 N.A. N.A. 29.4 N.A. N.A. N.A. 28.2 N.A. N.A. N.A.
Protein Similarity: 100 78.8 41.3 52.2 N.A. 94 41.4 N.A. N.A. 39.8 N.A. N.A. N.A. 37 N.A. N.A. N.A.
P-Site Identity: 100 20 6.6 13.3 N.A. 100 6.6 N.A. N.A. 13.3 N.A. N.A. N.A. 93.3 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 6.6 26.6 N.A. 100 40 N.A. N.A. 20 N.A. N.A. N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 25 25 0 0 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 50 0 13 13 13 13 0 0 0 38 0 50 0 13 % E
% Phe: 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 25 0 0 0 0 0 13 0 0 0 13 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % I
% Lys: 0 0 0 0 38 0 0 13 0 0 0 0 13 13 13 % K
% Leu: 13 0 0 38 13 0 13 0 50 0 13 75 0 0 0 % L
% Met: 13 0 0 13 0 0 0 0 0 0 0 0 0 0 13 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 13 25 13 0 13 50 25 25 13 0 13 13 25 38 13 % P
% Gln: 0 0 0 0 0 0 13 0 0 13 0 0 0 0 0 % Q
% Arg: 0 0 0 0 13 13 0 0 0 50 13 0 0 25 0 % R
% Ser: 0 13 0 25 13 25 38 25 0 0 13 0 0 13 0 % S
% Thr: 25 13 50 0 0 0 0 38 0 13 13 0 0 0 0 % T
% Val: 0 0 13 13 0 0 0 0 0 0 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 38 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _